This was Pope Paul II's home (1464), and one of the first buildings to use the Renaissance style in Rome (timidly). It has retained elements of Medieval fortresses. It became the residence of Venetian ambassadors, then later, Mussolini's office (the Duce used to harangue crowds, from here). Today, it houses a museum where you can see Medieval collections, such as: Christ Pantocrator in Byzantine enamel, or the Primitive Sienese and Florentine works of the Sterbini Collection...